Differences in Metal Ions Released from Orthodontic Appliances in an In Vitro and In Vivo Setting

The aim was to assess the composition of released metal ions from fixed orthodontic appliances both in an vitro and vivo setting compare their quantities evaluate any possible health risks associated with them. For setting, a set 24 as-received sterile SS brackets, 2 archwires, NiTi archwires were aged for 90 days artificial saliva, ion concentrations determined by inductively coupled plasma mass spectrometry (ICP-MS), using matrix-matched standards calibration. 15 SS, retrieved after intraoral exposure subjects. Debris on each part appliance assessed scanning electron microscopy energy dispersive spectroscopy (SEM/EDS). present study evidenced difference detected setting. Generally, relative content higher debris than that saliva. concentration all tested alloys below upper recommended limit daily intake; however, local effects terms hypersensitivity due accumulation cannot be excluded even such concentrations.